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. 2012 Mar 21;48(24):3018-20.
doi: 10.1039/c2cc17566e. Epub 2012 Feb 13.

Design of small molecule reagents that enable signal amplification via an autocatalytic, base-mediated cascade elimination reaction

Hemakesh Mohapatra  1 , Kyle M Schmid, Scott T Phillips
Affiliations

Design of small molecule reagents that enable signal amplification via an autocatalytic, base-mediated cascade elimination reaction

Hemakesh Mohapatra et al. Chem Commun (Camb). .

Abstract

This Communication describes three small molecule reagents that amplify the signal for a detection event via an autocatalytic reaction. Two signals are obtained from each reagent: (i) the dibenzofulvene chromophore and (ii) piperidine, which can be visualized using a pH indicator dye. The reagents are demonstrated in a model assay for palladium.

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