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Comparative Study
. 1990 Aug;7(4):365-9.

Sequence of a cDNA encoding human galactose-1-phosphate uridyl transferase

J E Flach  1 , J K Reichardt, L J Elsas 2nd
Affiliations
  • PMID: 2233247
Comparative Study

Sequence of a cDNA encoding human galactose-1-phosphate uridyl transferase

J E Flach et al. Mol Biol Med. 1990 Aug.

Abstract

We report a revised sequence of a cDNA that encodes a human galactose-1-phosphate uridyl transferase. The cDNA is 1295 bases in length and encodes a 43,000 Mr protein. The sequence was derived from a cDNA clone isolated from a transformed human lymphoblast cell line and amplified in a polymerase chain reaction. The revised sequence reveals a higher degree of amino acid conservation between the human enzyme and the homologous enzymes from Escherichia coli and yeast than was previously thought to exist.

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