Some lessons about models from Michaelis and Menten
- PMID: 22337858
- PMCID: PMC3279381
- DOI: 10.1091/mbc.E11-07-0643
Some lessons about models from Michaelis and Menten
Erratum in
- Mol Biol Cell. 2012 Jul;23(14):2819
Abstract
Michaelis and Menten's classic 1913 paper on enzyme kinetics is used to draw some lessons about the relationship between mathematical models and biological reality.
References
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- Anderson KS. Detection and characterization of enzyme intermediates: utility of rapid chemical quench methodology and single enzyme turnover experiments. In: Johnson KA, editor. In Kinetic Analysis of Macromolecules: A Practical Approach. Oxford: Oxford University Press; 2003. pp. 19–47.
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- Chance B. The kinetics of the enzyme-substrate compound of peroxidase. J Biol Chem. 1943;151:553–577. - PubMed
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