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Comment
. 2012 Apr 1;18(7):1821-3.
doi: 10.1158/1078-0432.CCR-12-0409. Epub 2012 Feb 15.

The antitumor immunity of ipilimumab: (T-cell) memories to last a lifetime?

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Comment

The antitumor immunity of ipilimumab: (T-cell) memories to last a lifetime?

Michael A Postow et al. Clin Cancer Res. .

Abstract

Ipilimumab has shown an overall survival benefit in 2 randomized phase III studies. A minority of patients achieve long-term disease control, highlighting the potential of this immunotherapeutic approach. In ongoing efforts, investigators are continuing to characterize these patients' unique clinical courses and correlate their responses with underlying mechanisms of antitumor immunity.

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