Case Reports
doi: 10.1002/mus.880131011.
Central changes in hypothyroid myopathy: a case report
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- PMID: 2233852
- DOI: 10.1002/mus.880131011
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Case Reports
Central changes in hypothyroid myopathy: a case report
Muscle Nerve.
1990 Oct.
Abstract
A muscle biopsy from a patient with hypothyroid myopathy showed striking central changes. "Cores" were seen in most type 1 fibers with oxidative enzyme preparations. Electron microscopy of these areas revealed Z disc streaming, myofilament disruption, and absent mitochondria. The myopathy rapidly improved with thyroxine treatment. This biopsy is of interest, as numerous "cores" have not previously been reported in hypothyroid myopathy.
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