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. 1990 Nov 8;348(6297):137-43.
doi: 10.1038/348137a0.

Requirement for hsp70 in the mitochondrial matrix for translocation and folding of precursor proteins

P J Kang  1 , J Ostermann, J Shilling, W Neupert, E A Craig, N Pfanner
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Free article

Requirement for hsp70 in the mitochondrial matrix for translocation and folding of precursor proteins

P J Kang et al. Nature. .
Free article

Abstract

By analysis of a temperature-sensitive yeast mutant, a heat-shock protein in the matrix of mitochondria, mitochondrial hsp70 (Ssc1p), is found to be involved both in translocation of nuclear-encoded precursor proteins across the mitochondrial membranes and in (re)folding of imported proteins in the matrix.

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