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Review
. 2012 Jul;14(7-8):573-83.
doi: 10.1016/j.micinf.2012.01.012. Epub 2012 Feb 4.

Streptococcus pneumoniae: the evolution of antimicrobial resistance to beta-lactams, fluoroquinolones and macrolides

J E Cornick  1 , S D Bentley
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Free article
Review

Streptococcus pneumoniae: the evolution of antimicrobial resistance to beta-lactams, fluoroquinolones and macrolides

J E Cornick et al. Microbes Infect. 2012 Jul.
Free article

Abstract

Multi drug resistant Streptococcus pneumoniae constitute a major public health concern worldwide. In this review we discuss how the transformable nature of the pneumococcus, in parallel with antimicrobial induced stress, contributes to the evolution of antimicrobial resistance; and how the introduction of the pneumococcal conjugate vaccine has affected the situation.

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