Comment on "Rapid cancer detection by topically spraying a γ-glutamyltranspeptidase-activated fluorescent probe"
- PMID: 22344683
- DOI: 10.1126/scitranslmed.3003686
Comment on "Rapid cancer detection by topically spraying a γ-glutamyltranspeptidase-activated fluorescent probe"
Abstract
A recent report from Urano et al. described the development of near-infrared (NIR) probes for cancer detection using chemical bioconjugation of targeting agents. Here, I highlight an alternative strategy to develop cancer-selective NIR imaging and theranostic agents without chemical conjugation.
Comment on
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Rapid cancer detection by topically spraying a γ-glutamyltranspeptidase-activated fluorescent probe.Sci Transl Med. 2011 Nov 23;3(110):110ra119. doi: 10.1126/scitranslmed.3002823. Sci Transl Med. 2011. PMID: 22116934 Free PMC article.
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