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Case Reports
. 2011 Sep;17(3):226-8.
doi: 10.4103/0971-6866.92099.

Refractory seizures with global developmental delay: A rare cause

P N Vinoth  1 , Betty Chacko, J Julius Xavier Scott, Venkatasai
Affiliations
Case Reports

Refractory seizures with global developmental delay: A rare cause

P N Vinoth et al. Indian J Hum Genet. 2011 Sep.

Abstract

Aicardi syndrome is a genetic disorder characterized by the triad of infantile spasm in flexion, callosal agenesis and ocular abnormalities (chorioretinal lacunae, coloboma of optic disc). We report a typical case of Aicardi syndrome with all the classical features.

Keywords: Callosal agenesis; chorioretinal lacunae; coloboma; infantile spasm.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
Computed tomography scan of the brain axial sections show parallel lateral ventricles, agenesis of corpus callosum and asymmetry of cerebral hemispheres
Figure 2
Figure 2
Computed tomography scan of the brain axial sections show agenesis of corpus callosum, asymmetry of cerebral hemispheres and pachygyria
Figure 3
Figure 3
Computed tomography scan of the brain axial sections show right arachnoid cyst
See this image and copyright information in PMC

References

    1. Aicardi J, Lefebvre J, Lerique-Koechlin A. A new syndrome: Spasms in flexion, callosal agenesis, ocular abnormalities. Electroencephalogr Clin Neurophysiol. 1965;19:609–10.
    1. Singhi PD, Gupta A, Agarwal A. Aicardi syndrome. Indian Pediatr. 1991;28:1513–6. - PubMed
    1. Ropers HH, Zuffardi O, Bianchi E, Tiepolo L. Agenesis of corpus callosum, ocular and skeletal anamalies (X linked dominant Aicardi's syndrome in a girl with balanced X/3 translocation) Hum Genet. 1982;61:364–8. - PubMed
    1. Hopkins IJ, Humphrey J, Keith CG, Sussman M, Webb GC, Turner EK. The Aicardi syndrome in a 47, XXY male. Aust Pediatr J. 1979;15:278–80. - PubMed
    1. Molina JA, Mateos F, Merino M, Epistefanio JL, Gorrono M. Aicardi syndrome in two sisters. J Pediatr. 1989;115:282–3. - PubMed

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