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. 2011 Oct;14(4):287-90.
doi: 10.4103/0972-2327.91951.

Design, data analysis and sampling techniques for clinical research

Karthik Suresh  1 , Sanjeev V Thomas, Geetha Suresh
Affiliations

Design, data analysis and sampling techniques for clinical research

Karthik Suresh et al. Ann Indian Acad Neurol. 2011 Oct.

Abstract

Statistical analysis is an essential technique that enables a medical research practitioner to draw meaningful inference from their data analysis. Improper application of study design and data analysis may render insufficient and improper results and conclusion. Converting a medical problem into a statistical hypothesis with appropriate methodological and logical design and then back-translating the statistical results into relevant medical knowledge is a real challenge. This article explains various sampling methods that can be appropriately used in medical research with different scenarios and challenges.

Keywords: Design; sampling; study.

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Conflict of interest statement

Conflict of Interest: Nil.

Figures

Figure 1
Figure 1
Overall framework of research design
See this image and copyright information in PMC

References

    1. De Gans J, de Beek VD. “Dexamethasone in Adults with Bacterial Menningitis”. N Engl J Med. 2002;324:1549–56. - PubMed
    1. Scarborough M, Gordon S, Whitty C, French N, Njale Y, Chitani A. “Corticosteroids for Bacterial Meningitis in Adults in Sub-Saharan Africa”. N Engl J Med. 2007;357:2441–50. - PMC - PubMed
    1. Holroyd KA, Cottrell CK, O’Donnell FJ, Drew JB, Carlson BW, Himawan L. “Effect of Preventive (β blocker) Treatment, behavioural Migraine Management or their combination on outcomes of optimized acute treatment in frequent migraine: Randomized controlled trial”. BMJ. 2010;341:c4871. - PMC - PubMed
    1. Golafshani N. Understanding reliability and validity in qualitative research. Qual Rep. 2003;8:597–607.
    1. Peace KE, Parrillo AV, Hardy JC. “Assessing the validity of statistical inferences in public health research: An Evidence – based ‘Best Practice’ approach”. J Georgia Public Health Assoc. 2008;1:1. Available from: http://faculty.mercer.edu/thomas_bm/documents/jgpha/documents/Archive/Pa... .