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. 2011 Sep;17(3):219-21.
doi: 10.4103/0973-1075.92339.

Hypofractionated radiotherapy as local hemostatic agent in advanced cancer

Malik Tariq Rasool  1 , Najmi Arshad Manzoor, Syed Arshad Mustafa, Lone Mohammad Maqbool, Fir Afroz
Affiliations

Hypofractionated radiotherapy as local hemostatic agent in advanced cancer

Malik Tariq Rasool et al. Indian J Palliat Care. 2011 Sep.

Abstract

Purpose: Tumor bleeding continues to remain a challenge in an oncological setting, and radiotherapy has been studied as a local hemostatic agent. We studied the role of local radiotherapy in controlling bleeding at our center.

Materials and methods: We reviewed 25 treated cases (cancer urinary bladder: 12, lung cancer: 5, cervical cancer: 4, uterine cancer: 1, rectal cancer: 2, schwanoma: 1) at our center from March 2008 to December 2010. All patients had either an advanced or recurrent disease. Radiotherapy schedule was either 20 Gray in 5 fractions or 15 Gray in 5 fractions and was delivered with Cobalt 60.

Results and conclusion: Of 25 patients, 22 (88%) responded, and there was complete cessation of bleeding. Both 15 Gray and 20 Gray dose schedule had equal efficacy. Treatment was well tolerated without any intermission. Radiotherapy is a safe and effective option in controlling tumor bleeding.

Keywords: Hemostasis; Hypofractionation; Radiotherapy.

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Conflict of interest statement

Conflict of Interest: None declared.

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References

    1. Pereira J, Mancini I, Bruera E. The management of bleeding in patients with advanced cancer. In: Portenoy RK, Bruera E, editors. Topics in Palliative Care. Vol. 4. New York: Oxford University Press; 2000. pp. 163–83.
    1. Srinivasan V, Brown CH, Turner AG. A comparison of two radiotherapy regimens for the treatment of symptoms from advanced bladder cancer. Clin Oncol (R Coll Radiol) 1994;6:11–3. - PubMed
    1. Hoskin PJ. In: Radiotherapy in symptom management. 2nd ed. Macdonald N, Hanks GW, Macdonald N, editors. Oxford University Press: New York; 1998. pp. 278–80.
    1. Brundage MD, Bezjak A, Dixon P, Grimard L, Larochelle M, Warde P, et al. The role of palliative thoracic radiotherapy in non-small cell lung cancer. Can J Oncol. 1996;6(Suppl 1):25–32. - PubMed
    1. Biswal BM, Lal P, Rath GK, Mohanti BK. Hemostatic radiotherapy in carcinoma of the uterine cervix. Int J Gynaecol Obstet. 1995;50:281–5. - PubMed