Diabetic macular edema: current and emerging therapies
- PMID: 22346109
- PMCID: PMC3277023
- DOI: 10.4103/0974-9233.92110
Diabetic macular edema: current and emerging therapies
Abstract
Diabetic macular edema is a leading cause of vision impairment among people within the working- age population. This review discusses the pathogenesis of diabetic macular edema and the treatment options currently available for the treatment of diabetic macular edema, including for focal/grid photocoagulation, intravitreal corticosteroids and intravitreal anti-vascular endothelial growth factor agents. The biologic rationale for novel therapeutic agents, many of which are currently being evaluated in clinical trials, also is reviewed.
Keywords: Diabetic Macular Edema; Focal/Grid Photocoagulation; Intravitreal Corticosteroids.
Conflict of interest statement
References
-
- World Health Organization Diabetes Fact Sheet Number 312. [cited in 2011]. Available from: http://www.who.int/mediacentre/factsheets/fs312/en/
-
- Moss SE, Klein R, Klein BE. The 14-year incidence of visual loss in a diabetic population. Ophthalmology. 1998;105:998–1003. - PubMed
-
- Klein R, Klein BE, Moss SE, Cruickshanks KJ. The Wisconsin Epidemiologic Study of Diabetic Retinopathy: XVII: The 14-year incidence and progression of diabetic retinopathy and associated risk factors in type 1 diabetes. Ophthalmology. 1998;105:1801–15. - PubMed
-
- Diabetes Control and Complications Trial Research Group. Progression of retinopathy with intensive versus conventional treatment in the Diabetes Control and Complications Trial. Ophthalmology. 1995;102:647–61. - PubMed
-
- Bhagat N, Grigorian RA, Tutela A, Zarbin MA. Diabetic macular edema: Pathogenesis and treatment. Surv Ophthalmol. 2009;54:1–32. - PubMed
LinkOut - more resources
Full Text Sources
Molecular Biology Databases
