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Case Reports
. 1997 Nov;8(6):347-50.
doi: 10.1155/1997/305246.

Disseminated Nocardia otitidiscaviarum in a patient with AIDS

Affiliations
Case Reports

Disseminated Nocardia otitidiscaviarum in a patient with AIDS

R M Sandre et al. Can J Infect Dis. 1997 Nov.

Abstract

A case of disseminated infection due to Nocardia otitidiscaviarum is described in a Caucasian man infected with the human immunodeficiency virus. The patient presented with no previous AIDS-defining conditions, a CD4 lymphocyte count of 206 cells/mm(3) and enlarging intra-abdominal and chest wall abscesses with bilateral pulmonary infiltrates. Aggressive surgical debridement and antimicrobial therapy with trimethoprim/sulfamethoxazole and amikacin resulted in clinical cure. Long term suppressive therapy was needed to prevent relapse.

Un cas d’infection disséminée à Nocardia otitidiscaviarum est décrit chez un homme de race blanche infecté au virus de l’immunodéficience humaine. Le patient s’est présenté sans maladie antérieure liée au diagnostic du sida, une numération des lymphocytes CD4 à 206 cellules/mm3 et des abcès intra-abdominaux et thoraciques en progression avec infiltrats pulmonaires bilatéraux. Un débridement chirurgical énergique et un traitement antibiotique par triméthoprime/sulfaméthoxazole et amikacine ont amené une guérison clinique. Le traitement suppressif prolongé a été nécessaire pour prévenir une rechute.

Keywords: AIDS; Human immunodeficiency virus; Nocardia otitidiscaviarum.

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Figures

Figure 1
Figure 1
Clinical photograph of the patient at the time of presentation demonstrating a large mass in the left uppper abdominal quadrant and chest wall
Figure 2
Figure 2
Augmented computed tomography revealing a large septated intra-abdominal mass
Figure 3
Figure 3
Chest radiograph of the patient postoperatively demonstrating extensive bilateral pulmonary involvement

References

    1. Uttamchandani RB, Daikos GL, Reyes RR, et al. Nocardiosis in 30 patients with advanced human immunodeficiency virus infection: Clinical features and outcome. Clin Infect Dis. 1994;18:348–53. - PubMed
    1. Coker RJ, Bignardi G, Horner P, et al. Nocardia infection in AIDS: A clinical and microbiological challenge. J Clin Pathol. 1992;45:821–2. - PMC - PubMed
    1. Sieratzki HJ. Nocardia brasiliensis infection in patients with AIDS. Clin Infect Dis. 1992;14:977–8. (Lett) - PubMed
    1. Mishra SK, Gordon RE, Barnett DA. Identification of nocardiae and streptomycetes of medical importance. J Clin Microbiol. 1980;11:728–36. - PMC - PubMed
    1. Lechevalier HA. Nocardioform actinomycetes In: Bergey’s Manual of Systematic Bacteriology. Vol. 4. Baltimore: Williams & Wilkins; 1989. pp. 2384–404.

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