Metformin-induced hepatotoxicity
- PMID: 22355024
- PMCID: PMC3322705
- DOI: 10.2337/dc11-2306
Metformin-induced hepatotoxicity
Similar articles
-
[Therapeutic renaissance. Biguanides in type-2 diabetes: metformin].Pharm Unserer Zeit. 2002;31(3):264-70. doi: 10.1002/1615-1003(200205)31:3<264::AID-PAUZ264>3.0.CO;2-D. Pharm Unserer Zeit. 2002. PMID: 12071123 Review. German. No abstract available.
-
Lactic acidosis associated (or induced by) metformin.Med Clin (Barc). 2017 Nov 9;149(9):415-416. doi: 10.1016/j.medcli.2017.07.009. Epub 2017 Sep 1. Med Clin (Barc). 2017. PMID: 28865920 English, Spanish. No abstract available.
-
Metformin in type 2 diabetes.J Fam Pract. 2004 Nov;53(11):900. J Fam Pract. 2004. PMID: 15527727 No abstract available.
-
Erythema multiforme from metformin.Ann Pharmacother. 2004 Sep;38(9):1537. doi: 10.1345/aph.1E074. Epub 2004 Jun 29. Ann Pharmacother. 2004. PMID: 15226487 No abstract available.
-
Metformin in 2019.JAMA. 2019 May 21;321(19):1926-1927. doi: 10.1001/jama.2019.3805. JAMA. 2019. PMID: 31009043 Free PMC article. Review.
Cited by
-
Literature review of the clinical characteristics of metformin-induced hepatotoxicity.Front Pharmacol. 2022 Sep 6;13:969505. doi: 10.3389/fphar.2022.969505. eCollection 2022. Front Pharmacol. 2022. PMID: 36147344 Free PMC article.
-
Tyrosine Kinase Inhibitors for the Treatment of Chronic-Phase Chronic Myeloid Leukemia: Long-Term Patient Care and Management.J Adv Pract Oncol. 2016 Jan-Feb;7(1):42-54. doi: 10.6004/jadpro.2016.7.1.3. Epub 2016 Jan 1. J Adv Pract Oncol. 2016. PMID: 27713843 Free PMC article. Review.
-
Identification of a metabolic biomarker panel in rats for prediction of acute and idiosyncratic hepatotoxicity.Comput Struct Biotechnol J. 2014 Aug 9;10(17):78-89. doi: 10.1016/j.csbj.2014.08.001. eCollection 2014 Jul. Comput Struct Biotechnol J. 2014. PMID: 25379137 Free PMC article.
-
Mitochondrial stress response in drug-induced liver injury.Mol Biol Rep. 2021 Oct;48(10):6949-6958. doi: 10.1007/s11033-021-06674-6. Epub 2021 Aug 25. Mol Biol Rep. 2021. PMID: 34432218 Review.
-
Metformin induces pyroptosis in leptin receptor-defective hepatocytes via overactivation of the AMPK axis.Cell Death Dis. 2023 Feb 3;14(2):82. doi: 10.1038/s41419-023-05623-4. Cell Death Dis. 2023. PMID: 36737598 Free PMC article.
References
-
- Cone CJ, Bachyrycz AM, Murata GH. Hepatotoxicity associated with metformin therapy in treatment of type 2 diabetes mellitus with nonalcoholic fatty liver disease. Ann Pharmacother 2010;44:1655–1659 - PubMed
-
- Danan G, Benichou C. Causality assessment of adverse reactions to drugs—I. A novel method based on the conclusions of international consensus meetings: application to drug-induced liver injuries. J Clin Epidemiol 1993;46:1323–1330 - PubMed
-
- Romero-Gómez M, Diago M, Andrade RJ, et al. ; Spanish Treatment of Resistance to Insulin in Hepatitis C Genotype 1 Group. Treatment of insulin resistance with metformin in naïve genotype 1 chronic hepatitis C patients receiving peginterferon alfa-2a plus ribavirin. Hepatology 2009;50:1702–1708 - PubMed
-
- Brackett CC. Clarifying metformin's role and risks in liver dysfunction. J Am Pharm Assoc (2003) 2010;50:407–410 - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical