Case Reports
[Extrapyramidal syndrome caused by moderate overdosage of domperidone. Description of a case]
[Article in
Italian]
Affiliations
- PMID: 2235667
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Case Reports
[Extrapyramidal syndrome caused by moderate overdosage of domperidone. Description of a case]
[Article in
Italian]
Pediatr Med Chir.
1990 Mar-Apr.
Abstract
Domperidone is useful in the treatment of vomiting and gastroesophageal reflux in children. Its efficaciousness is due to the antagonist effect on gastrointestinal dopaminergic receptors. Contrary to the initial expectations, domperidone is able to penetrate into the hematoencephalic barrier and to cause adverse neurologic reactions. We report a case of extrapyramidal reaction in a child after moderate overdosage of domperidone.
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