Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 1990 Mar-Apr;12(2):205-6.

[Extrapyramidal syndrome caused by moderate overdosage of domperidone. Description of a case]

[Article in Italian]
M Pellegrino  1 , M Sacco, F Lotti
Affiliations
  • PMID: 2235667
Case Reports

[Extrapyramidal syndrome caused by moderate overdosage of domperidone. Description of a case]

[Article in Italian]
M Pellegrino et al. Pediatr Med Chir. 1990 Mar-Apr.

Abstract

Domperidone is useful in the treatment of vomiting and gastroesophageal reflux in children. Its efficaciousness is due to the antagonist effect on gastrointestinal dopaminergic receptors. Contrary to the initial expectations, domperidone is able to penetrate into the hematoencephalic barrier and to cause adverse neurologic reactions. We report a case of extrapyramidal reaction in a child after moderate overdosage of domperidone.

PubMed Disclaimer