doi: 10.1007/BF00744323.
Erythropoietin processing in erythropoietic system and central nervous system
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- PMID: 22358640
- DOI: 10.1007/BF00744323
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Erythropoietin processing in erythropoietic system and central nervous system
Cytotechnology.
1995 Jan.
Abstract
We describe possible functions of carbohydrates attached to growth factors and strategies to examine the functions, concentrating on erythropoietin, a major regulator of erythropoiesis. Erythropoietin in erythropoiesis functions as an endocrine hormone; it is produced by kidney cells and transferred into the circulation to hemopoietic sites. In the brain, erythropoietin acts on neurons in a paracrine fashion. Comparison of glycosylation has been made between kidney and brain erythropoietins.
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