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. 1995 Jan;18(1-2):83-91.
doi: 10.1007/BF00744323.

Erythropoietin processing in erythropoietic system and central nervous system

M Nagao  1 , S Masuda, M Ueda, R Sasaki
Affiliations

Erythropoietin processing in erythropoietic system and central nervous system

M Nagao et al. Cytotechnology. 1995 Jan.

Abstract

We describe possible functions of carbohydrates attached to growth factors and strategies to examine the functions, concentrating on erythropoietin, a major regulator of erythropoiesis. Erythropoietin in erythropoiesis functions as an endocrine hormone; it is produced by kidney cells and transferred into the circulation to hemopoietic sites. In the brain, erythropoietin acts on neurons in a paracrine fashion. Comparison of glycosylation has been made between kidney and brain erythropoietins.

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