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. 1991 Feb;5(Suppl 1):152-7.
doi: 10.1007/BF00736836.

Role of interferons in cell differentiation and development

G Fiorucci  1 , G Romeo, G B Rossi
Affiliations

Role of interferons in cell differentiation and development

G Fiorucci et al. Cytotechnology. 1991 Feb.

Abstract

Interferons (IFNs), besides inducing an antiviral state in uninfected cells, are also natural regulatory molecules. They play a key role in the regulation both of cell growth and differentiation, and of development. Up-or down-regulation of oncogenes by IFNs may be one of the mechanisms by which these molecules affect cell physiology. The list of IFN-inducible proteins continues to grow rapidly and future research should identify among these the mediators of the biological effects of IFNs.

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