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. 2012 Jun;73(6):968-72.
doi: 10.1111/j.1365-2125.2012.04247.x.

Pharmacoeconomics

Dyfrig A Hughes  1
Affiliations

Pharmacoeconomics

Dyfrig A Hughes. Br J Clin Pharmacol. 2012 Jun.

Abstract

Pharmacoeconomics is an essential component of health technology assessment and the appraisal of medicines for use by UK National Health Service (NHS) patients. As a comparatively young discipline, its methods continue to evolve. Priority research areas for development include methods for synthesizing indirect comparisons when head-to-head trials have not been performed, synthesizing qualitative evidence (for example, stakeholder views), addressing the limitations of the EQ-5D tool for assessing quality of life, including benefits not captured in quality-adjusted life years (QALYs), ways of assessing valuation methods (for determining utility scores), extrapolation of costs and benefits beyond those observed in trials, early estimation of cost-effectiveness (including mechanism-based economic evaluation), methods for incorporating the impact of non-adherence and the role of behavioural economics in influencing patients and prescribers.

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Figures

Figure 1
Figure 1
A schematic representation of the components of a mechanism-based economic evaluation
See this image and copyright information in PMC

References

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