Comment
doi: 10.1016/j.neuron.2012.02.002.
Bers-ERK Schwann cells coordinate nerve regeneration
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- PMID: 22365537
- DOI: 10.1016/j.neuron.2012.02.002
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Comment
Bers-ERK Schwann cells coordinate nerve regeneration
Neuron.
.
Free article
Abstract
In this issue of Neuron, Napoli et al. (2012) demonstrate that elevated ERK/MAPK signaling in Schwann cells is a crucial trigger for Schwann cell dedifferentiation in vivo. Moreover, the authors show that dedifferentiated Schwann cells have the potential to coordinate much of the peripheral nerve response to injury.
Copyright © 2012 Elsevier Inc. All rights reserved.
Comment on
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A central role for the ERK-signaling pathway in controlling Schwann cell plasticity and peripheral nerve regeneration in vivo.Neuron. 2012 Feb 23;73(4):729-42. doi: 10.1016/j.neuron.2011.11.031. Neuron. 2012. PMID: 22365547
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