Regulatory T cells stay on course
- PMID: 22365661
- DOI: 10.1016/j.immuni.2012.02.004
Regulatory T cells stay on course
Abstract
Regulatory T (Treg) cells are thought to be susceptible to conversion into effector T cells. In this issue of Immunity, Miyao et al. (2012) provide evidence that the apparent plasticity of murine Foxp3(+) Treg cells is largely restricted to a defined subset of poorly committed Foxp3(+) cells.
Copyright © 2012 Elsevier Inc. All rights reserved.
Comment on
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Plasticity of Foxp3(+) T cells reflects promiscuous Foxp3 expression in conventional T cells but not reprogramming of regulatory T cells.Immunity. 2012 Feb 24;36(2):262-75. doi: 10.1016/j.immuni.2011.12.012. Epub 2012 Feb 9. Immunity. 2012. PMID: 22326580
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