Cytisine: a natural product lead for the development of drugs acting at nicotinic acetylcholine receptors

Abstract

Covering: up to the end of 2011. This review covers classical and modern structural modifications of the alkaloid, the more recent (since 2007) syntheses of cytisine and analogues, and the pharmacology of these compounds, with emphasis on their interactions with nicotinic receptors. 89 references are cited.