Scedosporium apiospermum endopthalmitis treated early with intravitreous voriconazole results in recovery of vision
- PMID: 22370908
- PMCID: PMC3438303
- DOI: 10.1007/s12348-012-0063-0
Scedosporium apiospermum endopthalmitis treated early with intravitreous voriconazole results in recovery of vision
Abstract
Aim: The purpose of this study is to report a case of endogenous endopthalmitis caused by Scedosporium apiospermum with a favorable outcome and review previously reported cases, their treatment regimens and outcomes.
Methods: An 83-year-old man with diabetes mellitus, no other immunocompromising risk factors, and a history of S. apiospermum endopthalmitis in the left eye developed endopthalmitis in the right eye. Within 72 h of presentation, he was treated with a pars plana vitrectomy and intravitreal voriconozole.
Results: Vitreous cultures confirmed S. apiospermum. The patient responded to treatment, with a favorable outcome and full recovery of vision.
Conclusions: Recognition of S. apiospermum endopthalmitis and appropriate early intervention with pars plana vitrectomy and intravitreal voriconozole can lead to a favorable outcome with restoration of visual acuity.
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References
-
- Cortez KJ, Roilides E, Quiroz-Telles F, Meletiadis J, Antachopoulos C, Knudsen T, Buchanan W, Milanovich J, Sutton DA, Fothergill A, Rinaldi MG, Shea YR, Zaoutis T, Kottilil S, Walsh TJ. Infections caused by Scedosporium spp. Clin Microbiol Rev. 2008;21(1):157–197. doi: 10.1128/CMR.00039-07. - DOI - PMC - PubMed
-
- Rippon JW. Petriellidiosis: the great imitator. Clin Microbiol Newletter. 1981;3:57–58. doi: 10.1016/S0196-4399(81)80067-0. - DOI
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