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. 2012 Sep;2(3):157-60.
doi: 10.1007/s12348-012-0063-0. Epub 2012 Feb 28.

Scedosporium apiospermum endopthalmitis treated early with intravitreous voriconazole results in recovery of vision

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Scedosporium apiospermum endopthalmitis treated early with intravitreous voriconazole results in recovery of vision

Monika Paroder Belenitsky et al. J Ophthalmic Inflamm Infect. 2012 Sep.

Abstract

Aim: The purpose of this study is to report a case of endogenous endopthalmitis caused by Scedosporium apiospermum with a favorable outcome and review previously reported cases, their treatment regimens and outcomes.

Methods: An 83-year-old man with diabetes mellitus, no other immunocompromising risk factors, and a history of S. apiospermum endopthalmitis in the left eye developed endopthalmitis in the right eye. Within 72 h of presentation, he was treated with a pars plana vitrectomy and intravitreal voriconozole.

Results: Vitreous cultures confirmed S. apiospermum. The patient responded to treatment, with a favorable outcome and full recovery of vision.

Conclusions: Recognition of S. apiospermum endopthalmitis and appropriate early intervention with pars plana vitrectomy and intravitreal voriconozole can lead to a favorable outcome with restoration of visual acuity.

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References

    1. Cortez KJ, Roilides E, Quiroz-Telles F, Meletiadis J, Antachopoulos C, Knudsen T, Buchanan W, Milanovich J, Sutton DA, Fothergill A, Rinaldi MG, Shea YR, Zaoutis T, Kottilil S, Walsh TJ. Infections caused by Scedosporium spp. Clin Microbiol Rev. 2008;21(1):157–197. doi: 10.1128/CMR.00039-07. - DOI - PMC - PubMed
    1. McGuire TW, Bullock JD, Bullock JD, Jr, Elder BL, Funkhouser JW. Fungal endophthalmitis. An experimental study with a review of 17 human ocular cases. Arch Ophthalmol. 1991;109(9):1289–1296. doi: 10.1001/archopht.1991.01080090115034. - DOI - PubMed
    1. Rippon JW. Petriellidiosis: the great imitator. Clin Microbiol Newletter. 1981;3:57–58. doi: 10.1016/S0196-4399(81)80067-0. - DOI
    1. Musk M, Chambers D, Chin W, Murray R, Gabbay E. Successful treatment of disseminated scedosporium infection in 2 lung transplant recipients: review of the literature and recommendations for management. J Heart Lung Transplant. 2006;25(10):1268–1272. doi: 10.1016/j.healun.2006.06.002. - DOI - PubMed
    1. Shankar S, Biswas J, Gopal L, Bagyalakshmi R, Therese L, Borse NJ. Anterior chamber exudative mass due to Scedosporium apiospermum in an immunocompetent individual. Indian J Ophthalmol. 2007;55(3):226–227. doi: 10.4103/0301-4738.31949. - DOI - PubMed

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