Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2012 Feb;12(1):90-1.
doi: 10.7861/clinmedicine.12-1-90.

Warfarin-induced skin necrosis

Affiliations
Case Reports

Warfarin-induced skin necrosis

Catherine R Mungalsingh et al. Clin Med (Lond). 2012 Feb.

Abstract

Warfarin-induced skin necrosis is a rare but serious complication of treatment with this commonly prescribed drug. This lesson presents the case of a patient with extensive skin necrosis after inappropriately prolonged warfarinisation and delayed recognition. The condition is briefly reviewed to highlight key features and risk factors.

PubMed Disclaimer

Figures

Fig 1.
Fig 1.
Multiple tender, malodorous necrotic lesions were found on the patient's trunks, limbs and face. Right panel: these were typically comprised an eschar with surrounding purpura. Approximately 20% of the patient's body surface area was eventually involved.

References

    1. Nazarian R, Van Cott E, Zembowicz A, Duncan LM. Warfarin-induced skin necrosis. J Am Acad Dermatol 2009; 61: 325–3210.1016/j.jaad.2008.12.039 - DOI - PubMed
    1. Mo J, Retzinger GS.Warfarin-induced skin necrosis. Lab lines–a publication of the Department of Pathology and Laboratory Medicine at the University of Cincinnati. 2001. p. 7.
    1. Pero M, Verma S, Espeso A, Griffiths M, Jani P. An unusual case of warfarin-induced pinna skin necrosis. J Laryngol Otol 2009; 123: 685–8 - PubMed
    1. Gelwix T, Beeson M. Warfarin-induced skin necrosis. Am J Emerg Med 1998; 165541–310.1016/S0735-6757(98)90015-8 - DOI - PubMed
    1. Essex DW, Wynn SS, Jin DK. Late onset warfain-induced skin necrosis: case report and review of the literature. Am J Hematol 1998; 57: 233–7 - PubMed

Publication types