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. 2011 Nov 22;5 Suppl 8(Suppl 8):O8.
doi: 10.1186/1753-6561-5-S8-O8. eCollection 2011.

Chromosome identification and its application in Chinese hamster ovary cells

Yihua Cao  1 , Shuichi Kimura  2 , Joon-Young Park  1 , Miyuki Yamatani  1 , Kohsuke Honda  1 , Hisao Ohtake  1 , Takeshi Omasa  3
Affiliations

Chromosome identification and its application in Chinese hamster ovary cells

Yihua Cao et al. BMC Proc. .
No abstract available

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Figures

Figure 1
Figure 1
The physical map of CHO DG44 cells and karyotypic comparison to primary Chinese hamster cells on the basis of BAC-FISH results. Homologous region of CHO DG44 to Chinese hamster were colored according to the estimated Chinese hamster chromosomes.
See this image and copyright information in PMC

References

    1. Puck TT. Development of the Chinese hamster ovary (CHO) cell for use in somatic cell genetics. New York: John Wiley; 1985.
    1. Kao FT, Puck TT. Genetics of somatic mammalian cells, VII. Induction and isolation of nutritional mutants in Chinese hamster cells. Proc Natl Acad Sci U S A. 1968;60(4):1275–1281. doi: 10.1073/pnas.60.4.1275. - DOI - PMC - PubMed
    1. Urlaub G, Chasin LA. Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity. Proc Natl Acad Sci U S A. 1980;77(7):4216–4220. doi: 10.1073/pnas.77.7.4216. - DOI - PMC - PubMed
    1. Griffin TJ, Seth G, Xie HW, Bandhakavi S, Hu WS. Advancing mammalian cell culture engineering using genome-scale technologies. Trends Biotechnol. 2007;25(9):401–408. doi: 10.1016/j.tibtech.2007.07.004. - DOI - PubMed
    1. Wurm FM. Production of recombinant protein therapeutics in cultivated mammalian cells. Nat Biotechnol. 2004;22(11):1393–1398. doi: 10.1038/nbt1026. - DOI - PubMed

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