Expansion of the lysine acylation landscape
- PMID: 22374739
- DOI: 10.1002/anie.201200316
Expansion of the lysine acylation landscape
Abstract
Leaving marks: the number of known posttranslational modifications for lysine has been expanded considerably. In addition to acetylation of side-chain amino functionalities of lysine residues in proteins, crotonylation, succinylation, and malonylation have now been identified as posttranslational modifications in histone and in non-histone proteins.
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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