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. 2012 Mar;18(3):502-6.
doi: 10.3201/eid1803.111278.

Hepatitis E virus infection in HIV-infected persons

Nancy F Crum-Cianflone  1 , Jennifer Curry, Jan Drobeniuc, Amy Weintrob, Michael Landrum, Anuradha Ganesan, William Bradley, Brian K Agan, Saleem Kamili; Infectious Disease Clinical Research Program HIV Working Group
Affiliations

Hepatitis E virus infection in HIV-infected persons

Nancy F Crum-Cianflone et al. Emerg Infect Dis. 2012 Mar.

Abstract

To determine whether hepatitis E virus (HEV) is a cause of hepatitis among HIV-infected persons, we evaluated 1985-2009 data for US military beneficiaries. Evidence of acute or prior HEV infection was detected for 7 (4%) and 5 (3%) of 194 HIV-infected persons, respectively. HEV might be a cause of acute hepatitis among HIV-infected persons.

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Figures

Figure 1
Figure 1
Testing strategy for acute hepatitis E virus (HEV) infection among US military beneficiaries who had had increased alanine aminotransferase (ALT) levels during 1985–2009. +, positive; –, negative.
Figure 2
Figure 2
IgM and IgG against hepatitis E virus (HEV) signal/cutoff ratios for 7 HIV-infected US military beneficiaries with acute HEV infection, 1985–2009. Serum specimens were tested for HEV markers before and after alanine aminotransferase spike, indicated by 0.0 on x-axis. Horizontal lines indicate enzyme immunoassay signal/cutoff ratio of 1.0.
See this image and copyright information in PMC

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