Nonculture diagnostic tests for enteric diseases
- PMID: 22377326
- PMCID: PMC3309642
- DOI: 10.3201/eid1803.111914
Nonculture diagnostic tests for enteric diseases
Abstract
The diagnosis of acute gastroenteritis (AGE) has traditionally been based on culture results of feces from patients with diarrhea. Virtually everything we know about disease and the epidemiology of enteric pathogens, such as Salmonella spp., Shiga toxin-producing Escherichia coli (STEC), e.g., O157, and Campylobacter spp., has been generated from the study of patients with culture-confirmed infections. However, this pattern may be changing because AGE diagnostics are moving away from culture toward rapid nonculture methods. These infections are mainly foodborne and therefore preventable, and it is of paramount importance that public health surveillance for these infections is consistent and reliable.
Comment on
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Laboratory practices and incidence of non-O157 shiga toxin-producing Escherichia coli infections.Emerg Infect Dis. 2012 Mar;18(3):477-9. doi: 10.3201/eid1803.111358. Emerg Infect Dis. 2012. PMID: 22377034 Free PMC article.
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Culturing stool specimens for Campylobacter spp., Pennsylvania, USA.Emerg Infect Dis. 2012 Mar;18(3):484-7. doi: 10.3201/eid1803.111266. Emerg Infect Dis. 2012. PMID: 22377086 Free PMC article.
References
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- Gould LH, Bopp C, Strockbine N, Atkinson R, Baselski V, Body B, et al. Recommendations for diagnosis of Shiga toxin–producing Escherichia coli infections by clinical laboratories. MMWR Recomm Rep. 2009;58:1–14. - PubMed
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- Centers for Disease Control and Prevention. Shiga toxin-producing Escherichia coli; 2005 case definition. 2009. [cited 2011 Dec 19]. http://www.cdc.gov/osels/ph_surveillance/nndss/casedef/shiga_current.htm
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