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Comment
. 2012 Mar;66(2):159-60.
doi: 10.1016/j.biopha.2011.09.009. Epub 2011 Dec 31.

Splenectomy as a therapeutic approach in refractory hemophagocytic lymphohistiocytosis

Comment

Splenectomy as a therapeutic approach in refractory hemophagocytic lymphohistiocytosis

Maciej Machaczka. Biomed Pharmacother. 2012 Mar.

Abstract

Zhang et al. have reported a case of an adult man with hemophagocytic lymphohistiocytosis (HLH) with an unknown etiology who has achieved a remission of HLH following comprehensive treatment based on splenectomy. In the present communication, the author critically discusses diagnostic and therapeutic issues related to the reported case, and questions utility of splenectomy in the treatment of active HLH.

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