Chemokines and chemokine receptors in susceptibility to HIV-1 infection and progression to AIDS
- PMID: 22377730
- PMCID: PMC3826810
- DOI: 10.3233/DMA-2011-0874
Chemokines and chemokine receptors in susceptibility to HIV-1 infection and progression to AIDS
Abstract
A multitude of host genetic factors plays a crucial role in susceptibility to HIV-1 infection and progression to AIDS, which is highly variable among individuals and populations. This review focuses on the chemokine-receptor and chemokine genes, which were extensively studied because of their role as HIV co-receptor or co-receptor competitor and influences the susceptibility to HIV-1 infection and progression to AIDS in HIV-1 infected individuals.
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