Metabolism: unmasking an oncometabolite
- PMID: 22378191
- DOI: 10.1038/nrc3248
Metabolism: unmasking an oncometabolite
Comment on
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IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype.Nature. 2012 Feb 15;483(7390):479-83. doi: 10.1038/nature10866. Nature. 2012. PMID: 22343889 Free PMC article.
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Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation.Nature. 2012 Feb 15;483(7390):484-8. doi: 10.1038/nature10898. Nature. 2012. PMID: 22343896 Free PMC article.
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IDH mutation impairs histone demethylation and results in a block to cell differentiation.Nature. 2012 Feb 15;483(7390):474-8. doi: 10.1038/nature10860. Nature. 2012. PMID: 22343901 Free PMC article.
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