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Editorial
. 2012 Mar 6;59(10):962-4.
doi: 10.1016/j.jacc.2011.11.031.

Neural remodeling and myocardial infarction: the stellate ganglion as a double agent

Olujimi A Ajijola, Kalyanam Shivkumar
Editorial

Neural remodeling and myocardial infarction: the stellate ganglion as a double agent

Olujimi A Ajijola et al. J Am Coll Cardiol. .
No abstract available

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Figures

Figure 1
Figure 1. Cardiac-Neuraxial Pathways of Sympathetic Nerve Signaling and Remodeling After Myocardial Infarction
Major elements of the cardiac neural axis with known and unknown directions of nerve traffic after myocardial infarction. Intramyocardial nerve injury signals reach the cardiac neural axis via direct neural impulses, nerve growth factor (NGF) (or other signaling molecules) transported via axons or circulatory system. These afferent signals reach the left (and right) stellate ganglion, resulting in anatomic remodeling within the stellates and increased efferent nerve signals back to the heart via intracardiac neurons and the cardiac neuronal network. It is unknown whether the spinal cord and higher brain centers also participate in this process and remodel after significant cardiac injury.
See this image and copyright information in PMC

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