Review
doi: 10.3949/ccjm.79a.11082.
Protease inhibitors: silver bullets for chronic hepatitis C infection?
Affiliations
- PMID: 22383557
- DOI: 10.3949/ccjm.79a.11082
Item in Clipboard
Review
Protease inhibitors: silver bullets for chronic hepatitis C infection?
Cleve Clin J Med.
2012 Mar.
Free article
Abstract
Recent trials evaluated the safety and efficacy of two protease inhibitors, boceprevir (Victrelis) and telaprevir (Incivek), added to standard care with pegylated interferon and ribavirin, in patients with chronic hepatitis C virus (HCV) infection. These drugs open the door for triple therapy and other new therapies involving combinations of other direct-acting antiviral agents to become the new standard of care for this population.
Similar articles
-
Telaprevir (Incivek) and boceprevir (Victrelis) for chronic hepatitis C.Med Lett Drugs Ther. 2011 Jul 25;53(1369):57-9. Med Lett Drugs Ther. 2011. PMID: 21778964 No abstract available.
-
Triple therapy with first generation HCV protease inhibitors: lead-in or no lead-in phase?J Hepatol. 2013 Feb;58(2):391-4. doi: 10.1016/j.jhep.2012.09.023. Epub 2012 Oct 9. J Hepatol. 2013. PMID: 23063419
-
Impact of ribavirin on HCV replicon RNA decline during treatment with interferon-α and the protease inhibitors boceprevir or telaprevir.Antivir Ther. 2011;16(5):695-704. doi: 10.3851/IMP1821. Antivir Ther. 2011. PMID: 21817191
-
Impact of HCV protease-inhibitor-based triple therapy for chronic HCV genotype 1 infection.Antivir Ther. 2011;16(8):1187-201. doi: 10.3851/IMP1934. Antivir Ther. 2011. PMID: 22155901 Review.
-
The role of triple therapy with protease inhibitors in hepatitis C virus genotype 1 naïve patients.Liver Int. 2011 Jan;31 Suppl 1:53-7. doi: 10.1111/j.1478-3231.2010.02391.x. Liver Int. 2011. PMID: 21205138 Review.
Cited by
-
Hepatitis C seroprevalence among prison inmates since 2001: still high but declining.Public Health Rep. 2014 Mar-Apr;129(2):187-95. doi: 10.1177/003335491412900213. Public Health Rep. 2014. PMID: 24587554 Free PMC article.
-
Genetic variants at the IFNL3 locus and their association with hepatitis C virus infections reveal novel insights into host-virus interactions.J Interferon Cytokine Res. 2014 Jul;34(7):479-97. doi: 10.1089/jir.2013.0113. Epub 2014 Feb 20. J Interferon Cytokine Res. 2014. PMID: 24555572 Free PMC article. Review.
-
Rapid virological response of telaprevir and boceprevir in a Brazilian cohort of HCV genotype 1 patients: a multicenter longitudinal study.Ther Clin Risk Manag. 2017 Jan 10;13:59-64. doi: 10.2147/TCRM.S124663. eCollection 2017. Ther Clin Risk Manag. 2017. PMID: 28138248 Free PMC article.
-
SiO2-Ag Composite as a Highly Virucidal Material: A Roadmap that Rapidly Eliminates SARS-CoV-2.Nanomaterials (Basel). 2021 Mar 4;11(3):638. doi: 10.3390/nano11030638. Nanomaterials (Basel). 2021. PMID: 33806671 Free PMC article.
-
Serine Proteases of Malaria Parasite Plasmodium falciparum: Potential as Antimalarial Drug Targets.Interdiscip Perspect Infect Dis. 2014;2014:453186. doi: 10.1155/2014/453186. Epub 2014 Mar 11. Interdiscip Perspect Infect Dis. 2014. PMID: 24799897 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
