Special stem cells for bone
- PMID: 22385649
- DOI: 10.1016/j.stem.2012.02.012
Special stem cells for bone
Abstract
Mesenchymal stem cells (MSCs) are multipotential in vitro, but their endogenous properties are poorly defined. In this issue of Cell Stem Cell, Park et al. (2012) report that an MSC-like, osteolineage-directed Mx1+ population generates new osteoblasts at sites of bone damage, suggesting its potential for skeletal repair and regeneration.
Copyright © 2012 Elsevier Inc. All rights reserved.
Comment on
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Endogenous bone marrow MSCs are dynamic, fate-restricted participants in bone maintenance and regeneration.Cell Stem Cell. 2012 Mar 2;10(3):259-72. doi: 10.1016/j.stem.2012.02.003. Cell Stem Cell. 2012. PMID: 22385654 Free PMC article.
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