Comment
doi: 10.1016/j.stem.2012.02.011.
iPSCs to the rescue in Alzheimer's research
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- PMID: 22385650
- DOI: 10.1016/j.stem.2012.02.011
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iPSCs to the rescue in Alzheimer's research
Cell Stem Cell.
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Free article
Abstract
A crucial limitation to our understanding of Alzheimer's disease has been the inability to test hypotheses on live, patient-specific neurons. A recent study in Nature by Israel et al. (2012) reports that iPSC-derived neurons from AD patients recapitulate multiple aspects of disease pathology.
Copyright © 2012 Elsevier Inc. All rights reserved.
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Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells.Nature. 2012 Jan 25;482(7384):216-20. doi: 10.1038/nature10821. Nature. 2012. PMID: 22278060 Free PMC article.
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