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Review
. 2012 Apr;6(2):196-203.
doi: 10.1016/j.molonc.2012.01.009. Epub 2012 Feb 16.

Moving molecular targeted drug therapy towards personalized medicine: issues related to clinical trial design

Jaap Verweij  1 , Maja de Jonge, Ferry Eskens, Stefan Sleijfer
Affiliations
Review

Moving molecular targeted drug therapy towards personalized medicine: issues related to clinical trial design

Jaap Verweij et al. Mol Oncol. 2012 Apr.

Abstract

With the event of new Molecular targets, clinical trial design requirements to perform these trials are changing. This paper discusses some of the considerations that need to be taken into account when designing a trial, including those trials that assess combinations of targets.

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