Population genomics: an investigative tool for epidemics
- PMID: 22386771
- PMCID: PMC3378846
- DOI: 10.1016/j.ajpath.2012.01.007
Population genomics: an investigative tool for epidemics
Abstract
This Commentary highlights the article by Fittipaldi et al describing the emergence and epidemic spread of an emm59 strain of group A streptococcus.
Comment on
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Full-genome dissection of an epidemic of severe invasive disease caused by a hypervirulent, recently emerged clone of group A Streptococcus.Am J Pathol. 2012 Apr;180(4):1522-34. doi: 10.1016/j.ajpath.2011.12.037. Epub 2012 Feb 11. Am J Pathol. 2012. PMID: 22330677
References
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- McGregor K., Bilek N., Bennett A., Kalia A., Beall B., Carapetis J., Currie B., Sriprakash K., Spratt B., Bessen D. Group A streptococci from a remote community have novel multilocus genotypes but share emm types and housekeeping alleles with isolates from worldwide sources. J Infect Dis. 2004;189:717–723. - PubMed
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- Fittipaldi N., Beres S.B., Olsen R.J., Kapur V., Shea P.R., Watkins M.E., Cantu C.C., Laucirica D.R., Jenkins L., Flores A.R., Lovgren M., Ardanuy C., Liñares J., Low D.E., Tyrrell G.J., Musser J.M. Full-genome dissection of an epidemic of severe invasive disease caused by a hypervirulent, recently emerged clone of group A Streptococcus. Am J Pathol. 2012;180:1522–1534. - PubMed
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- Steer A.C., Law I., Matatolu L., Beall B.W., Carapetis J.R. Global emm type distribution of group A streptococci: systematic review and implications for vaccine development. Lancet Infect Dis. 2009;9:611–616. - PubMed
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