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Review
. 2012 Aug 1;524(1):30-42.
doi: 10.1016/j.abb.2012.02.013. Epub 2012 Mar 3.

Giving the right tug for migration: cadherins in tissue movements

Sarah F Becker  1 , Rahul Langhe, Chaolie Huang, Doris Wedlich, Jubin Kashef
Affiliations
Review

Giving the right tug for migration: cadherins in tissue movements

Sarah F Becker et al. Arch Biochem Biophys. .

Abstract

Dynamically regulated cell-cell adhesion is crucial for morphogenesis during embryonic development and tumor progression. The cadherins as calcium-dependent cell-cell adhesion proteins represent key molecules in these tissue movements. How cadherins serve in maintaining tissue cohesion during migration, facilitate cell-cell communication and promote signaling will be summarized in this review.

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