Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2012 May 1;125(17):2165-70.
doi: 10.1161/CIRCULATIONAHA.112.092924. Epub 2012 Mar 2.

National Heart, Lung, and Blood Institute Workshop: improving outcomes for pulmonary vascular disease

Affiliations

National Heart, Lung, and Blood Institute Workshop: improving outcomes for pulmonary vascular disease

Ivan M Robbins et al. Circulation. .
No abstract available

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Pediatric pulmonary hypertensive vascular disorders often have multiple factors that contribute to the severity of pulmonary vascular disease.
Figure 2.
Figure 2.
Pulmonary vascular disease may result from epigenetic and genetic factors, prenatal exposures, or postnatal insults that produce sustained alterations of vascular signaling pathways in children and adults. PVD indicates pulmonary vascular disease; IUGR, intrauterine growth retardation.
Figure 3.
Figure 3.
Clinical research designed to understand the longitudinal course of pulmonary vascular disease development will identify disorders and abnormalities contributing to pulmonary vascular dysfunction. Better diagnostic criteria and phenotyping will result, ultimately leading to better therapeutic responses. Understanding the presymptomatic phase of pulmonary vascular disease might also identify interventions to prevent disease onset, especially in the pediatric population.

References

    1. Simonneau G, Robbins IM, Beghetti M, Channick RN, Delcroix M, Denton CP, Elliott CG, Gaine SP, Gladwin MT, Jing ZC, Krowka MJ, Langleben D, Nakanishi N, Souza R. Updated clinical classification of pulmonary hypertension. J Am Coll Cardiol. 2009;54:S43–S54. - PubMed
    1. Cerro MJ, Abman S, Diaz G, Freudenthal AH, Freudenthal F, Harikrishnan S, Haworth SG, Ivy D, Lopes AA, Raj JU, Sandoval J, Stenmark K, Adatia I. A consensus approach to the classification of pediatric pulmonary hypertensive vascular disease: Report from the PVRI Pediatric Taskforce, Panama 2011. Pulm Circ. 2011;1:286–298. - PMC - PubMed
    1. Humbert M, Sitbon O, Chaouat A, Bertocchi M, Habib G, Gressin V, Yaici A, Weitzenblum E, Cordier JF, Chabot F, Dromer C, Pison C, Reynaud-Gaubert M, Haloun A, Laurent M, Hachulla E, Simonneau G. Pulmonary arterial hypertension in France: results from a national registry. Am J Respir Crit Care Med. 2006;173:1023–1030. - PubMed
    1. Machado RD, Eickelberg O, Elliott CG, Geraci MW, Hanaoka M, Loyd JE, Newman JH, Phillips JA III, Soubrier F, Trembath RC, Chung WK. Genetics and genomics of pulmonary arterial hypertension. J Am Coll Cardiol. 2009;54:S32–S42. - PMC - PubMed
    1. Mathai SC, Hassoun PM. Pulmonary arterial hypertension associated with systemic sclerosis. Expert Rev Respir Med. 2011;5:267–279. - PMC - PubMed

Publication types

MeSH terms