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. 2012 Jun;14(6):399-404.
doi: 10.1177/1098612X12441317. Epub 2012 Mar 2.

Potassium iodide capsule treatment of feline sporotrichosis

Erica G Reis  1 , Isabella D F Gremião, Amanda A B Kitada, Raphael F D B Rocha, Verônica S P Castro, Mônica B L Barros, Rodrigo C Menezes, Sandro A Pereira, Tânia M P Schubach
Affiliations

Potassium iodide capsule treatment of feline sporotrichosis

Erica G Reis et al. J Feline Med Surg. 2012 Jun.

Abstract

Sporotrichosis is a mycosis caused by Sporothrix schenckii. The most affected animal is the cat; it has played an important role in the zoonotic transmission of this disease, especially in Rio de Janeiro, Brazil, since 1998. In order to evaluate the treatment of feline sporotrichosis with potassium iodide, an observational cohort was conducted in 48 cats with sporotrichosis at Instituto de Pesquisa Clínica Evandro Chagas, Fiocruz. All cats received potassium iodide capsules, 2.5 mg/kg to 20 mg/kg q24h. The cure rate was 47.9%, treatment failure was 37.5%, treatment abandonment was 10.4% and death was 4.2%. Clinical adverse effects were observed in 52.1% of the cases. Thirteen cats had a mild increase in hepatic transaminase levels during the treatment, six of them presented clinical signs suggestive of hepatotoxicity. Compared to previous studies with itraconazole and iodide in saturated solution, potassium iodide capsules are an alternative for feline sporotrichosis treatment.

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Conflict of interest statement

The authors do not have any potential conflicts of interest to declare.

Figures

Figure 1
Figure 1
(A,C) Cats with ulcerated cutaneous lesions caused by Sporotrix schenckii before treatment. (B,D) The cats after KI treatment — the lesions have resolved
Figure 2
Figure 2
Median doses used at inclusion and discharge in 48 cats with sporotrichosis treated with KI capsules
See this image and copyright information in PMC

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