Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2011:2011:325826.
doi: 10.5402/2011/325826. Epub 2011 Oct 3.

Esophageal involvement in scleroderma: clinical, endoscopic, and manometric features

M Lahcene  1 , N Oumnia, N Matougui, M Boudjella, A Tebaibia, B Touchene
Affiliations

Esophageal involvement in scleroderma: clinical, endoscopic, and manometric features

M Lahcene et al. ISRN Rheumatol. 2011.

Abstract

Aim. To evaluate characteristics of esophageal involvement in scleroderma. Methods. The study was prospective and concerned 194 patients with a definite systemic sclerosis. Gastroesophageal endoscopy and esophageal manometry were performed in all the cases. Results. Symptoms were present in 118 cases (60.8%); they were signs of GERD or dysphagia, respectively, in 94 (48.4%) and 91 patients (46.9%). Reflux esophagitis was found in 73 cases (37.6%); it was mild or moderate in 47 cases (24.2%) and severe or complicated in the remaining cases. Manometry revealed a lower esophageal sphincter incompetence and esophageal motor disorders, respectively, in 118 (60.8%) and 157 cases (80.9%). Presence of these late was not related to age, duration, or skin extension of the disease, but with clinical complaint and/or mucosal damage. Conclusion. Esophageal involvement is frequent during scleroderma. Manometry is the most sensible examination and could be a screening procedure.

PubMed Disclaimer

References

    1. Hostein J, Fournet J. Gastrointestinal manifestations of collagen diseases. Digestive Diseases and Sciences. 1986;4(4):240–252. - PubMed
    1. Lock G, Holstege A, Lang B, Schölmerich J. Gastrointestinal manifestations of progressive systemic sclerosis. The American Journal of Gastroenterology. 1997;92(5):763–771. - PubMed
    1. Rose S, Young MA, Reynolds JC. Gastrointestinal manifestations of scleroderma. Gastroenterology Clinics of North America. 1998;27(3):563–594. - PubMed
    1. Sjögren RW. Gastrointestinal motility disorders in scleroderma. Arthritis and Rheumatism. 1994;37(9):1265–1282. - PubMed
    1. Akesson A, Wollheim FA. Organ manifestations in 100 patients with progressive systemic sclerosis: a comparison between the CREST syndrome and diffuse scleroderma. The British Journal of Rheumatology. 1989;28(4):281–286. - PubMed

LinkOut - more resources