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. 2011:2011:805646.
doi: 10.5402/2011/805646. Epub 2011 Nov 30.

Targeting fatigue in stroke patients

Andrew W Barritt  1 , David G Smithard
Affiliations

Targeting fatigue in stroke patients

Andrew W Barritt et al. ISRN Neurol. 2011.

Abstract

Symptoms of fatigue are often reported by patients in both the acute and chronic stages of recovery following a stroke. It is commonly associated with low mood and sleep disturbances, but can arise in their absence. However, it has also been associated with poorer long-term outcome and, as such, its aetiology warrants a greater understanding. There is convincing evidence that inflammatory cascades and cytokine signalling precipitated by the infarct promote fatigue, and these pathways may harbour therapeutic targets in its management.

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References

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