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Randomized Controlled Trial
. 2012 Feb;102(2):336-42.
doi: 10.2105/AJPH.2011.300357. Epub 2011 Dec 15.

Outcomes of a Latino community-based intervention for the prevention of diabetes: the Lawrence Latino Diabetes Prevention Project

Ira S Ockene  1 , Trinidad L Tellez, Milagros C Rosal, George W Reed, John Mordes, Philip A Merriam, Barbara C Olendzki, Garry Handelman, Robert Nicolosi, Yunsheng Ma
Affiliations
Randomized Controlled Trial

Outcomes of a Latino community-based intervention for the prevention of diabetes: the Lawrence Latino Diabetes Prevention Project

Ira S Ockene et al. Am J Public Health. 2012 Feb.

Abstract

Objectives: We tested the effectiveness of a community-based, literacy-sensitive, and culturally tailored lifestyle intervention on weight loss and diabetes risk reduction among low-income, Spanish-speaking Latinos at increased diabetes risk.

Methods: Three hundred twelve participants from Lawrence, Massachusetts, were randomly assigned to lifestyle intervention care (IC) or usual care (UC) between 2004 and 2007. The intervention was implemented by trained Spanish-speaking individuals from the community. Each participant was followed for 1 year.

Results: The participants' mean age was 52 years; 59% had less than a high school education. The 1-year retention rate was 94%. Compared with the UC group, the IC group had a modest but significant weight reduction (-2.5 vs 0.63 lb; P = .04) and a clinically meaningful reduction in hemoglobin A1c (-0.10% vs -0.04%; P = .009). Likewise, insulin resistance improved significantly in the IC compared with the UC group. The IC group also had greater reductions in percentage of calories from total and saturated fat.

Conclusions: We developed an inexpensive, culturally sensitive diabetes prevention program that resulted in weight loss, improved HbA1c, and improved insulin resistance in a high-risk Latino population.

Trial registration: ClinicalTrials.gov NCT00810290.

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Figures

FIGURE 1—
FIGURE 1—
Study participation and follow-up rates: Lawrence Latino Diabetes Prevention Project, 2004–2007.
FIGURE 2—
FIGURE 2—
Association of weight loss with session attendance: Lawrence Latino Diabetes Prevention Project, 2004–2007.
See this image and copyright information in PMC

References

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