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Multicenter Study
. 2012 May 26;138(15):656-9.
doi: 10.1016/j.medcli.2011.10.027. Epub 2012 Mar 6.

[Anemia in heart failure: its usefulness as prognosis or comorbidity marker: GESAIC-2 study]

[Article in Spanish]
Jorge Grau-Amorós  1 , Francesc Formiga, Oscar Aramburu, Jesús Recio-Iglesias, Joan Carles Trullàs, Agustín Urrutia
Affiliations
Multicenter Study

[Anemia in heart failure: its usefulness as prognosis or comorbidity marker: GESAIC-2 study]

[Article in Spanish]
Jorge Grau-Amorós et al. Med Clin (Barc). .

Abstract

Background and objective: To assess the prognosis and etiology of anemia in heart failure (HF).

Patients and methods: Prospective multicenter cohort of HF after one year of hospitalization.

Results: A total of 57 (27%) of the 211 patients died and 115 (67.8%) were readmitted. Mortality was higher in the group with anemia (31.8%) without statistical significance (P=.09), except for refractory HF mortality (P=.013). Predictors of HF mortality included Barthel index (hazard ratio [HR] 0.97, CI 95% 0.96 to 0.98) and serum creatinine at discharge (HR 2.28, 95% CI 1.51 to 3.45). For reentry, the Charlson index (OR 1.16, CI 95% 0.98 to 1.38), treatment with calcium channel blockers (OR 0.29, 95% CI 0.1 to 0.84) and not being treated with digoxin (OR 2.33, CI 95% 1.09 to 4.97), the latter with the greatest influence on readmission for HF (OR 3.07, CI 95% 1.39 to 6.79), along with not being a HF debut (OR 2.8, CI 95% 1.45 to 5.39).

Conclusions: Anemia is an increased risk of mortality due to refractory HF, but not for readmission within the first year after an acute event.

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