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Case Reports
. 2012 Jun;6(5):610-6.
doi: 10.1016/j.crohns.2011.12.007. Epub 2012 Jan 26.

Infliximab-induced psoriasis during therapy for Crohn's disease

Flavio Steinwurz  1 , Rafael Denadai, Rogério Saad-Hossne, Maria Luiza Queiroz, Fábio Vieira Teixeira, Ricardo Romiti
Affiliations
Case Reports

Infliximab-induced psoriasis during therapy for Crohn's disease

Flavio Steinwurz et al. J Crohns Colitis. 2012 Jun.

Abstract

Although therapy with tumor necrosis factor-alpha inhibitors (anti-TNF) provides beneficial effects in different immune inflammatory disorders, paradoxical cases of anti-TNF-induced psoriasis have increasingly been reported, mostly in the setting of rheumatologic diseases. To date, less than 50 cases of infliximab-induced psoriasis in inflammatory bowel disease patients have been described. The present report was aimed at describing two new cases of infliximab-induced psoriasis during therapy for Crohn's disease and at carrying out a review on this intriguing phenomenon.

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