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Case Reports
. 2012;5(2):179-81.
Epub 2012 Feb 12.

Primary diffuse large B-cell lymphoma of the submandibular gland

Tadashi Terada
Case Reports

Primary diffuse large B-cell lymphoma of the submandibular gland

Tadashi Terada. Int J Clin Exp Pathol. 2012.
No abstract available

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Figures

Figure 1
Figure 1
MRI features. A large tumor is seen in the left submandibular gland.
Figure 2
Figure 2
Histological features. A. Diffuse atypical lymphoid cell proliferation is seen. The lymphoid cells are invasive into the striated muscles. HE, x20. B. The atypical cells have hyperchromatic nuclei and occasional nucleoli. Some mitotic figures and apoptotic cells are seen. HE, x400.
Figure 3
Figure 3
Immunohistochemical features. The tumor cells are positive for CD45 (A) and CD20 (B). They are diffusely positive for p53 protein (95%) (C). The Ki-67 labeling is 100% (D). The tumor cells are positive for ƛ-chain (E), but not κ-chain. x400.
See this image and copyright information in PMC

References

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    1. Jaffe ES, Harris NL, Stein H, Vardiman JW, editors. Pathology and Genetics of tumors of haematopoietic and lymphoid system. Ryon: IARC Press; 2001. WHO Classification of tumour.
    1. Terada T, Kawaguchi M, Furukawa K, Sekido Y, Osamura Y. Minute mixed ductalendocrine carcinoma of the pancreas with predominant intraductal growth. Pathol Int. 2002;52:740–746. - PubMed
    1. Terada T, Kawaguchi M. Primary clear cell adenocarcinoma of the peritoneum. Tohoku J Exp Med. 2005;206:271–275. - PubMed
    1. Gleeson MJ, Bennett MH, Cawson RA. Lymphomas of salivary glands. Cancer. 1986;58:699–704. - PubMed

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