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Case Reports
. 2012 Mar 11:11:6.
doi: 10.1186/1476-0711-11-6.

Successful salvage therapy with Daptomycin for osteomyelitis caused by methicillin-resistant Staphylococcus aureus in a renal transplant recipient with Fabry-Anderson disease

Ennio Polilli  1 , Tamara Ursini, Elena Mazzotta, Federica Sozio, Vincenzo Savini, Domenico D'Antonio, Michelino Barbato, Augusta Consorte, Giustino Parruti
Affiliations
Case Reports

Successful salvage therapy with Daptomycin for osteomyelitis caused by methicillin-resistant Staphylococcus aureus in a renal transplant recipient with Fabry-Anderson disease

Ennio Polilli et al. Ann Clin Microbiol Antimicrob. .

Abstract

Daptomycin is licensed in adults for the management of Staphylococcus aureus methicillin-resistant infections, including bone and skin complicated infections. We describe for the first time its use in a renal transplant recipient for Fabry-Anderson Disease with right heel osteomyelitis. The patient was unresponsive to first-line Teicoplanin and second-line Tigecycline, whereas he was successfully treated with third-line Daptomycin monotherapy at 4 mg/Kg/qd for 4 weeks. Local debridement was performed in advance of each line of treatment.

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Figures

Figure 1
Figure 1
a) Ulcerative lesion of the right heel; b) Standard Rx scan of the right heel at patient entry.
Figure 2
Figure 2
Standard Rx scan of the right heel at end of treatment.
See this image and copyright information in PMC

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