Irisin, turning up the heat
- PMID: 22405065
- DOI: 10.1016/j.cmet.2012.02.010
Irisin, turning up the heat
Abstract
Exercise exerts beneficial effects on systemic metabolism. A recent Nature paper (Boström et al., 2012) identifies irisin as an exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin promotes brown adipocyte recruitment in white fat and improves systemic metabolism by increasing energy expenditure.
Copyright © 2012 Elsevier Inc. All rights reserved.
Comment on
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A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis.Nature. 2012 Jan 11;481(7382):463-8. doi: 10.1038/nature10777. Nature. 2012. PMID: 22237023 Free PMC article.
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