. 2012 Mar 12:12:59.

doi: 10.1186/1472-6963-12-59.

Engaging HIV-HCV co-infected patients in HCV treatment: the roles played by the prescribing physician and patients' beliefs (ANRS CO13 HEPAVIH cohort, France)

Dominique Salmon-Ceron¹, Julien Cohen, Maria Winnock, Perrine Roux, Firouze Bani Sadr, Eric Rosenthal, Isabelle Poizot Martin, Marc-Arthur Loko, Marion Mora, Philippe Sogni, Bruno Spire, François Dabis, Maria Patrizia Carrieri; HEPAVIH group

Collaborators, Affiliations

Collaborators

HEPAVIH group:
D Salmon, F Dabis, M Winnock, M A Loko, P Sogni, Y Benhamou, P Trimoulet, J Izopet, V Paradis, B Spire, P Carrieri, C Katlama, G Pialoux, I Poizot-Martin, B Marchou, E Rosenthal, A Bicart See, M Bentata, A Gervais, C Lascoux-Combe, C Goujard, K Lacombe, C Duvivier, D Vittecoq, D Neau, P Morlat, F BaniSadr, L Meyer, F Boufassa, S Dominguez, B Autran, A M Roque, C Solas, H Fontaine, G Chêne, D Costagliola, L Allain, D Salmon, F Dabis, M Winnock, Y Benhamou, P Sogni, J Izopet, P Trimoulet, B Spire, M P Carrieri, M Mora, J Cohen, P Roux, M Winnock, M A Loko, D Salmon, G Spiridon, F Almasi, O Eldbouni, P Sogni, C Katlama, M A Valantin, S Dominguez, Y Benhamou, A Gastaut, I Poizot-Martin, O Zaegel, G Pialoux, P Bonnard, F Bani-sadr, B Marchou, K Barange, S Metivier, E Rosenthal, C Pradier, A Krivitzky, M Bentata, M Uzan, A Bicart-See, D Garipuy, P Yéni, A Gervais, D Séréni, P M Girard, K Lacombe, J F Delfraissy, C Goujard, D Vittecoq, O Lortholary, C Duvivier, S Boucly, D Neau, P Morlat, I Raymond, I Louis, D Beniken, A Ivanova, A Fooladi, M Azar, P Honoré, S Breau, L Serini, M Mole, M Malet, C Bolliot, J Delaune, A Maignan, S Gillet, L Dequae Merchadou, E Pambrun, A Frosch, J Cohen, V Villes, P Kurkdji, M A Loko, M Winnock

Affiliation

¹ Unité de Maladies Infectieuses, Pôle Médecine, Hôpital COCHIN, Paris, France.

PMID: 22409788
PMCID: PMC3325848
DOI: 10.1186/1472-6963-12-59

Engaging HIV-HCV co-infected patients in HCV treatment: the roles played by the prescribing physician and patients' beliefs (ANRS CO13 HEPAVIH cohort, France)

Dominique Salmon-Ceron et al. BMC Health Serv Res. 2012.

. 2012 Mar 12:12:59.

doi: 10.1186/1472-6963-12-59.

Authors

Collaborators

HEPAVIH group:
D Salmon, F Dabis, M Winnock, M A Loko, P Sogni, Y Benhamou, P Trimoulet, J Izopet, V Paradis, B Spire, P Carrieri, C Katlama, G Pialoux, I Poizot-Martin, B Marchou, E Rosenthal, A Bicart See, M Bentata, A Gervais, C Lascoux-Combe, C Goujard, K Lacombe, C Duvivier, D Vittecoq, D Neau, P Morlat, F BaniSadr, L Meyer, F Boufassa, S Dominguez, B Autran, A M Roque, C Solas, H Fontaine, G Chêne, D Costagliola, L Allain, D Salmon, F Dabis, M Winnock, Y Benhamou, P Sogni, J Izopet, P Trimoulet, B Spire, M P Carrieri, M Mora, J Cohen, P Roux, M Winnock, M A Loko, D Salmon, G Spiridon, F Almasi, O Eldbouni, P Sogni, C Katlama, M A Valantin, S Dominguez, Y Benhamou, A Gastaut, I Poizot-Martin, O Zaegel, G Pialoux, P Bonnard, F Bani-sadr, B Marchou, K Barange, S Metivier, E Rosenthal, C Pradier, A Krivitzky, M Bentata, M Uzan, A Bicart-See, D Garipuy, P Yéni, A Gervais, D Séréni, P M Girard, K Lacombe, J F Delfraissy, C Goujard, D Vittecoq, O Lortholary, C Duvivier, S Boucly, D Neau, P Morlat, I Raymond, I Louis, D Beniken, A Ivanova, A Fooladi, M Azar, P Honoré, S Breau, L Serini, M Mole, M Malet, C Bolliot, J Delaune, A Maignan, S Gillet, L Dequae Merchadou, E Pambrun, A Frosch, J Cohen, V Villes, P Kurkdji, M A Loko, M Winnock

Affiliation

¹ Unité de Maladies Infectieuses, Pôle Médecine, Hôpital COCHIN, Paris, France.

PMID: 22409788
PMCID: PMC3325848
DOI: 10.1186/1472-6963-12-59

Abstract

Background: Treatment for the hepatitis C virus (HCV) may be delayed significantly in HIV/HCV co-infected patients. Our study aims at identifying the correlates of access to HCV treatment in this population.

Methods: We used 3-year follow-up data from the HEPAVIH ANRS-CO13 nationwide French cohort which enrolled patients living with HIV and HCV. We included pegylated interferon and ribavirin-naive patients (N = 600) at enrolment. Clinical/biological data were retrieved from medical records. Self-administered questionnaires were used for both physicians and their patients to collect data about experience and behaviors, respectively.

Results: Median [IQR] follow-up was 12[12-24] months and 124 patients (20.7%) had started HCV treatment. After multiple adjustment including patients' negative beliefs about HCV treatment, those followed up by a general practitioner working in a hospital setting were more likely to receive HCV treatment (OR[95%CI]: 1.71 [1.06-2.75]). Patients followed by general practitioners also reported significantly higher levels of alcohol use, severe depressive symptoms and poor social conditions than those followed up by other physicians.

Conclusions: Hospital-general practitioner networks can play a crucial role in engaging patients who are the most vulnerable and in reducing existing inequities in access to HCV care. Further operational research is needed to assess to what extent these models can be implemented in other settings and for patients who bear the burden of multiple co-morbidities.

PubMed Disclaimer

Figures

**Figure 1**
**Distribution of patients according to the specialty of their hospital physician**.

See this image and copyright information in PMC

References

1. Benhamou Y, Bochet M, Di Martino V, Charlotte F, Azria F, Coutellier A, Vidaud M, Bricaire F, Opolon P, Katlama C, Poynard T. Liver fibrosis progression in human immunodeficiency virus and hepatitis C virus coinfected patients. The Multivirc Group. Hepatology. 1999;30:1054–1058. doi: 10.1002/hep.510300409. - DOI - PubMed
1. Lewden C, May T, Rosenthal E, Burty C, Bonnet F, Costagliola D, Jougla E, Semaille C, Morlat P, Salmon D. et al.Changes in causes of death among adults infected by HIV between 2000 and 2005: The "Mortalite 2000 and 2005" surveys (ANRS EN19 and Mortavic) J Acquir Immune Defic Syndr. 2008;48:590–598. doi: 10.1097/QAI.0b013e31817efb54. - DOI - PubMed
1. Rosenthal E, Salmon-Ceron D, Lewden C, Bouteloup V, Pialoux G, Bonnet F, Karmochkine M, May T, Francois M, Burty C. et al.Liver-related deaths in HIV-infected patients between 1995 and 2005 in the French GERMIVIC Joint Study Group Network (Mortavic 2005 study in collaboration with the Mortalite 2005 survey, ANRS EN19) HIV Med. 2009;10:282–289. doi: 10.1111/j.1468-1293.2008.00686.x. - DOI - PubMed
1. Salmon-Ceron D, Lewden C, Morlat P, Bevilacqua S, Jougla E, Bonnet F, Heripret L, Costagliola D, May T, Chene G. Liver disease as a major cause of death among HIV infected patients: role of hepatitis C and B viruses and alcohol. J Hepatol. 2005;42:799–805. doi: 10.1016/j.jhep.2005.01.022. - DOI - PubMed
1. Weber R, Sabin CA, Friis-Moller N, Reiss P, El-Sadr WM, Kirk O, Dabis F, Law MG, Pradier C, De Wit S. et al.Liver-related deaths in persons infected with the human immunodeficiency virus: the D:A:D study. Arch Intern Med. 2006;166:1632–1641. - PubMed

Publication types

Actions

MeSH terms

Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions

LinkOut - more resources

Full Text Sources
Medical
- ClinicalTrials.gov
- MedlinePlus Health Information

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

Engaging HIV-HCV co-infected patients in HCV treatment: the roles played by the prescribing physician and patients' beliefs (ANRS CO13 HEPAVIH cohort, France)

Collaborators

Affiliation

Engaging HIV-HCV co-infected patients in HCV treatment: the roles played by the prescribing physician and patients' beliefs (ANRS CO13 HEPAVIH cohort, France)

Authors

Collaborators

Affiliation

Abstract

Figures

References

Publication types

MeSH terms

LinkOut - more resources

Full Text Sources

Medical